Supplementary Materials: Quercetin attenuates manganese-induced neuroinflammation by alleviating oxidative stress through regulation of apoptosis, iNOS/NF-κB and HO-1/Nrf2 pathways
نویسندگان
چکیده
manganese-induced neuroinflammation by alleviating oxidative stress through regulation of apoptosis, iNOS/NF-κB and HO-1/Nrf2 pathways Entaz Bahar 1, Ji-Ye Kim 2, 3, and Hyonok Yoon 1,* 1 College of Pharmacy, Research Institute of Pharmaceutical Sciences, Gyeongsang National University, Jinju 52828, Gyeongnam, Republic of Korea; [email protected] 2 Department of Pathology, College of Medicine, Yonsei University, Seoul 03722, Republic of Korea; [email protected] 3 Department of Pathology and Translational Genomics, School of Medicine, Samsung Medical Center, Seoul 06351, Republic of Korea, [email protected]
منابع مشابه
Quercetin Attenuates Manganese-Induced Neuroinflammation by Alleviating Oxidative Stress through Regulation of Apoptosis, iNOS/NF-κB and HO-1/Nrf2 Pathways
Manganese (Mn) is an essential trace element required for the development of human body and acts as an enzyme co-factor or activator for various reactions of metabolism. While essential in trace amounts, excessive Mn exposure can result in toxic accumulations in human brain tissue and resulting extrapyramidal symptoms called manganism similar to idiopathic Parkinson's disease (PD). Quercetin (Q...
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